State of the art in restless legs syndrome therapy: Practice recommendations for treating restless legs syndrome
Identifieur interne : 002B61 ( Main/Exploration ); précédent : 002B60; suivant : 002B62State of the art in restless legs syndrome therapy: Practice recommendations for treating restless legs syndrome
Auteurs : Wolfgang H. Oertel [Allemagne] ; Claudia Trenkwalder [Allemagne] ; Marco Zucconi [Italie] ; Heike Benes [Allemagne] ; Diego Garcia Borreguero [Espagne] ; Claudio Bassetti [Suisse] ; Markku Partinen [Finlande] ; Luigi Ferini-Strambi [Italie] ; Karin Stiasny-Kolster [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Recommandation.
English descriptors
- KwdEn :
- Algorithms, Dopamine Agents (therapeutic use), Dopamine agonist, Humans, Iron (deficiency), Iron (therapeutic use), Levodopa, Nervous system diseases, RLS, Recommendation, Restless Legs Syndrome (drug therapy), Restless legs syndrome, Review, State of the art, Treatment, dopamine agonist, levodopa, opiod, therapy.
- MESH :
- chemical , deficiency : Iron.
- chemical , therapeutic use : Dopamine Agents, Iron.
- drug therapy : Restless Legs Syndrome.
- Algorithms, Humans.
Abstract
Dopaminergic agents are the best‐studied agents and are considered first‐line treatment of restless legs syndrome (RLS). Extensive data are available for levodopa, pramipexole, and ropinirole, which have approval for the indication RLS, and to a smaller extent for cabergoline, pergolide, and rotigotine. Apart from one recent study, comparing two active drugs (levodopa and cabergoline), no comparative studies have been published. The individual treatment regimen with the most appropriate agent concerning efficacy and side effects has to be selected by the treating physician. On the basis of these clinical trials and expert opinion of the authors, a treatment algorithm is proposed to support the search for the optimal individual treatment. Opioids and anticonvulsants such as gabapentine are second‐line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 μg/L). © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21545
Affiliations:
- Allemagne, Espagne, Finlande, Italie, Suisse
- Canton de Zurich, Communauté de Madrid, District de Giessen, Hesse (Land), Lombardie
- Madrid, Marbourg, Milan, Zurich
- Université de Zurich
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Le document en format XML
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Oertel</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Philipps‐University, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Paracelsus‐Elena Hospital, Center of Parkinsonism and Movement Disorders, Kassel, University of Goettingen</wicri:regionArea><wicri:noRegion>University of Goettingen</wicri:noRegion><wicri:noRegion>University of Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Zucconi, Marco" sort="Zucconi, Marco" uniqKey="Zucconi M" first="Marco" last="Zucconi">Marco Zucconi</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, Vita‐Salute San Raffaele University, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Benes, Heike" sort="Benes, Heike" uniqKey="Benes H" first="Heike" last="Benes">Heike Benes</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Somni Bene Institute for Medical Research and Sleep Medicine Schwerin Ltd., Schwerin</wicri:regionArea><wicri:noRegion>Schwerin</wicri:noRegion><wicri:noRegion>Schwerin</wicri:noRegion></affiliation></author><author><name sortKey="Borreguero, Diego Garcia" sort="Borreguero, Diego Garcia" uniqKey="Borreguero D" first="Diego Garcia" last="Borreguero">Diego Garcia Borreguero</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundacion Jimenez Diaz, Universidad Autónoma, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bassetti, Claudio" sort="Bassetti, Claudio" uniqKey="Bassetti C" first="Claudio" last="Bassetti">Claudio Bassetti</name><affiliation wicri:level="4"><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neurology, University of Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Partinen, Markku" sort="Partinen, Markku" uniqKey="Partinen M" first="Markku" last="Partinen">Markku Partinen</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Skogby Sleep Clinic, Rinnekoti Research Centre, Espoo</wicri:regionArea><wicri:noRegion>Espoo</wicri:noRegion></affiliation></author><author><name sortKey="Ferini Trambi, Luigi" sort="Ferini Trambi, Luigi" uniqKey="Ferini Trambi L" first="Luigi" last="Ferini-Strambi">Luigi Ferini-Strambi</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, Vita‐Salute San Raffaele University, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Stiasny Olster, Karin" sort="Stiasny Olster, Karin" uniqKey="Stiasny Olster K" first="Karin" last="Stiasny-Kolster">Karin Stiasny-Kolster</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Philipps‐University, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007">2007</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">S18</biblScope><biblScope unit="supplement">S18</biblScope><biblScope unit="page" from="S466">S466</biblScope><biblScope unit="page" to="S475">S475</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">168D4E6C8C9721468DC3E586723A594CDFC2ED9D</idno><idno type="DOI">10.1002/mds.21545</idno><idno type="ArticleID">MDS21545</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Algorithms</term><term>Dopamine Agents (therapeutic use)</term><term>Dopamine agonist</term><term>Humans</term><term>Iron (deficiency)</term><term>Iron (therapeutic use)</term><term>Levodopa</term><term>Nervous system diseases</term><term>RLS</term><term>Recommendation</term><term>Restless Legs Syndrome (drug therapy)</term><term>Restless legs syndrome</term><term>Review</term><term>State of the art</term><term>Treatment</term><term>dopamine agonist</term><term>levodopa</term><term>opiod</term><term>therapy</term></keywords><keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Iron</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Dopamine Agents</term><term>Iron</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Restless Legs Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Algorithms</term><term>Humans</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Article synthèse</term><term>Etat actuel</term><term>Lévodopa</term><term>Pathologie du système nerveux</term><term>Recommandation</term><term>Stimulant dopaminergique</term><term>Syndrome des jambes sans repos</term><term>Traitement</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Recommandation</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dopaminergic agents are the best‐studied agents and are considered first‐line treatment of restless legs syndrome (RLS). Extensive data are available for levodopa, pramipexole, and ropinirole, which have approval for the indication RLS, and to a smaller extent for cabergoline, pergolide, and rotigotine. Apart from one recent study, comparing two active drugs (levodopa and cabergoline), no comparative studies have been published. The individual treatment regimen with the most appropriate agent concerning efficacy and side effects has to be selected by the treating physician. On the basis of these clinical trials and expert opinion of the authors, a treatment algorithm is proposed to support the search for the optimal individual treatment. Opioids and anticonvulsants such as gabapentine are second‐line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 μg/L). © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Espagne</li><li>Finlande</li><li>Italie</li><li>Suisse</li></country><region><li>Canton de Zurich</li><li>Communauté de Madrid</li><li>District de Giessen</li><li>Hesse (Land)</li><li>Lombardie</li></region><settlement><li>Madrid</li><li>Marbourg</li><li>Milan</li><li>Zurich</li></settlement><orgName><li>Université de Zurich</li></orgName></list><tree><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Oertel, Wolfgang H" sort="Oertel, Wolfgang H" uniqKey="Oertel W" first="Wolfgang H." last="Oertel">Wolfgang H. Oertel</name></region><name sortKey="Benes, Heike" sort="Benes, Heike" uniqKey="Benes H" first="Heike" last="Benes">Heike Benes</name><name sortKey="Stiasny Olster, Karin" sort="Stiasny Olster, Karin" uniqKey="Stiasny Olster K" first="Karin" last="Stiasny-Kolster">Karin Stiasny-Kolster</name><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name></country><country name="Italie"><region name="Lombardie"><name sortKey="Zucconi, Marco" sort="Zucconi, Marco" uniqKey="Zucconi M" first="Marco" last="Zucconi">Marco Zucconi</name></region><name sortKey="Ferini Trambi, Luigi" sort="Ferini Trambi, Luigi" uniqKey="Ferini Trambi L" first="Luigi" last="Ferini-Strambi">Luigi Ferini-Strambi</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Borreguero, Diego Garcia" sort="Borreguero, Diego Garcia" uniqKey="Borreguero D" first="Diego Garcia" last="Borreguero">Diego Garcia Borreguero</name></region></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Bassetti, Claudio" sort="Bassetti, Claudio" uniqKey="Bassetti C" first="Claudio" last="Bassetti">Claudio Bassetti</name></region></country><country name="Finlande"><noRegion><name sortKey="Partinen, Markku" sort="Partinen, Markku" uniqKey="Partinen M" first="Markku" last="Partinen">Markku Partinen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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